Quality of life of pediatric patients with atopic dermatitis and their caregivers.

To compare the quality of life (QoL) of children with and without atopic dermatitis (AD) and that of their caregivers and to assess their QoL according to different degrees of AD. This is a cross-sectional, case-control study conducted with patients aged between 4 and 12 years with and without AD and their caregivers. Patients were treated at the Pediatric Dermatology Outpatient Center and the Childcare Center of the Joana de Gusmão Children's Hospital, respectively, from June 2021 to March 2022. The QoL Assessment Scale Autoquestionnaire Qualité de Vie Infant Imagé (AUQEI) was applied to children and adolescents with AD and the control group while the World Health Organization Quality of Life assessment instrument was administered to their caregivers. Fifty cases and fifty controls were included in this study. When assessing the QoL of the case and control groups, statistically significant differences were found in the domains of the AUQUEI instrument. Regarding QoL and AD severity, a statistically significant difference was seen (p = 0.027) when comparing moderate and severe SCORAD scores. When comparing the QoL of children with and without AD, a difference was seen between the two groups. The QoL of AD patients was worse and related to the severity of the disease. A better QoL was found among the caregivers in the control group. In the case group, the higher the SCORAD score, the worse the QoL. No relationship was found between AD severity and the QoL of the caregivers in the case group.

Assessment of mHealth Solutions Applied to Fall Detection for the Elderly.

Mobile Health has been increasingly present in healthcare due to the wide availability of applications for smartphones, however, robust assessment methods must be considered, seeking to provide evidence for clinical practice and mHealth solutions. This research presents the assessment of applications aimed at detecting and preventing falls for the elderly, available for Android and IOS, through the Mobile App Rating Scale. Based on the results presented, it can be concluded that the fall detection and prevention applications for the elderly available for Android and IOS showed good quality after rigorous evaluation.

Meta-Analysis of Sensorimotor Gating Deficits in Patients With Schizophrenia Evaluated by Prepulse Inhibition Test.

Prepulse inhibition (PPI) of startle is an operational measure of sensorimotor gating that is often impaired in patients with schizophrenia. Despite the large number of studies, there is considerable variation in PPI outcomes reported. We conducted a systematic review and meta-analysis investigating PPI impairment in patients with schizophrenia compared with healthy control subjects, and examined possible explanations for the variation in results between studies. Major databases were screened for observational studies comparing healthy subjects and patients with schizophrenia for the prepulse and pulse intervals of 60 and 120 ms as primary outcomes, ie, PPI-60 and PPI-120. Standardized mean difference (SMD) and 95% confidence intervals (CI) were extracted and pooled using random effects models. We then estimated the mean effect size of these measures with random effects meta-analyses and evaluated potential PPI heterogeneity moderators, using sensitivity analysis and meta-regressions. Sixty-seven primary studies were identified, with 3685 healthy and 4290 patients with schizophrenia. The schizophrenia group showed reduction in sensorimotor gating for both PPI-60 (SMD = -0.50, 95% CI = [-0.61, -0.39]) and PPI-120 (SMD = -0.44, 95% CI = [-0.54, -0.33]). The sensitivity and meta-regression analysis showed that sample size, gender proportion, imbalance for gender, source of control group, and study continent were sources of heterogeneity (P < .05) for both PPI-60 and PPI-120 outcomes. Our findings confirm a global sensorimotor gating deficit in schizophrenia patients, with overall moderate effect size for PPI-60 and PPI-120. Methodological consistency should decrease the high level of heterogeneity of PPI results between studies.

Meta-Analysis of the Sensitivity of Decision Support Systems in Diagnosing Diabetic Retinopathy.

Diabetic Retinopathy (DR) is one of the most common microvascular complications presenting by patients diagnosticated with diabetic diseases. Uncontrolled hyperglycemia may manifest as visual impairment and blindness. The early detection of DR is essential to minimize the risk and consequence of visual diminishing. The standard gold diagnoses tool relies on different imaging modalities and requires a judgment of expert photographers, which are not available in most of the primary care centers or remote location. In that scenario, an automate or semiautomated DR screening systems can contribute to improving the accuracy of the diagnostic. Thus, we performed a Systematic Review and Meta-Analysis to evaluate the Decision Support Systems (DSS) in diagnosing DR. The overall Diagnostic Odds Ratio was 73.15 (95%CI: 37.54-142.50), sensitivity was 97.70 (95%CI: 97.50-97.90) and specificity was 90.30 (95%CI: 90.00-90.60). Our results corroborate with the concept of usefulness of DSSs in early diagnosis, screening and preliminary evaluation of suspicious images of DR.

Análise subjetiva de fatores pré-oncogênicos em pacientes com neoplasias de cabeça e pescoço, de um hospital do sul catarinense / Subjective analysis of pre-oncogenic factors in head and neck cancer in a hospital in Santa Catarina

Introdução: Mais de 550 mil casos de tumor de cabeça e pescoço surgem anualmente, e estes constituem a 5ª neoplasia mais prevalente no mundo. As neoplasias de cabeça e pescoço tem etiologia multifatorial, onde se destacam como principais agentes pre-oncologicos, segundo a literatura, o tabaco, álcool, HPV, exposição ao sol e o próprio envelhecimento. As lesões neoplásicas geralmente são detectadas tardiamente por serem assintomáticas, e em decorrência disso os tumores são descobertos em uma fase muito avançada, deixando graves sequelas e um baixo índice de sobrevida. Métodos: Aplicaram-se questionários em 35 pacientes com diagnostico de tumor de cabeça e pescoço, e em 35 pacientes sem neoplasias diagnosticadas. O questionário avaliou os fatores pre-oncogenicos de cada grupo. Resultados: Observou-se dentre os pacientes com neoplasia: 71,4% sendo do sexo masculino; 94,3% caucasianos; 77,1% tendo histórico de câncer na família; 73,5% já fizeram uso de tabaco; 37,1% foram etilistas e 86,7% tiveram um alto índice de radiação solar. Já no grupo de pacientes sem neoplasias, foi observado: 45,7% sendo do sexo masculino; 82,9% caucasianos; 65,7% tendo histórico de câncer na família; 39,3% fizeram uso de tabaco; 8,6% foram etilistas e 44,1% tiveram um alto índice de radiação solar. Conclusão: Mediante o que foi pesquisado, pode-se afirmar que a maioria dos pacientes com neoplasias possuíam fatores pre-oncogenicos elevados. Já no grupo sem neoplasias diagnosticadas, encontrou-se um índice menor durante a pesquisa.

Introduction: More than 550.000 cases of head and neck tumors are discovered annually, being the 5th most prevalent neoplasm in the world. The number of tumor cases has been steadily increasing over the last few years around the world. The head and neck neoplasms have a multifactorial etiology, in which tobacco, alcohol, HPV, exposure to the sun and aging standout as the main pre-oncological agents. Neoplastic lesions are usually discovered too late, since they are asymptomatic, and as a result tumors are discovered at a very advanced stage, leaving severe sequelae and a low survival rate. Methods: Questionnaires were applied to 35 patients with diagnosis of head and neck tumors and to 35 patients without diagnosed neoplasms. This questionnaire evaluated the pre-oncogenic factors of each group. Results: It was observed among the patients with neoplasia: 71.4% were male; 94.3% Caucasians; 77.1% reported having a family history of cancer; 73.5% of patients have used tobacco; 37.1% reported having already been alcoholic drinker sand 86.7% had a high index of solar radiation. In the group of patients without neoplasias, 45.7% were male; 82.9% Caucasians; 65.7% reported having a family history of cancer; 39.3% of the patients have already used tobacco; 8.6% reported having already been alcoholic drinker sand 44.1% had a high index of solar radiation. Conclusion: Based on this search, it can be stated that the majority of patients with neoplasias had high pre-oncogenic factors. In the group without diagnosed neoplasms, a lower index was found during the study.

Injured Achilles Tendons Treated with Adipose-Derived Stem Cells Transplantation and GDF-5.

Tendon injuries represent a clinical challenge in regenerative medicine because their natural repair process is complex and inefficient. The high incidence of tendon injuries is frequently associated with sports practice, aging, tendinopathies, hypertension, diabetes mellitus, and the use of corticosteroids. The growing interest of scientists in using adipose-derived mesenchymal stem cells (ADMSC) in repair processes seems to be mostly due to their paracrine and immunomodulatory effects in stimulating specific cellular events. ADMSC activity can be influenced by GDF-5, which has been successfully used to drive tenogenic differentiation of ADMSC in vitro. Thus, we hypothesized that the application of ADMSC in isolation or in association with GDF-5 could improve Achilles tendon repair through the regulation of important remodeling genes expression. Lewis rats had tendons distributed in four groups: Transected (T), transected and treated with ADMSC (ASC) or GDF-5 (GDF5), or with both (ASC+GDF5). In the characterization of cells before application, ADMSC expressed the positive surface markers, CD90 (90%) and CD105 (95%), and the negative marker, CD45 (7%). ADMSC were also differentiated in chondrocytes, osteoblast, and adipocytes. On the 14th day after the tendon injury, GFP-ADMSC were observed in the transected region of tendons in the ASC and ASC+GDF5 groups, and exhibited and/or stimulated a similar genes expression profile when compared to the in vitro assay. ADMSC up-regulated Lox, Dcn, and Tgfb1 genes expression in comparison to T and ASC+GDF5 groups, which contributed to a lower proteoglycans arrangement, and to a higher collagen fiber organization and tendon biomechanics in the ASC group. The application of ADMSC in association with GDF-5 down-regulated Dcn, Gdf5, Lox, Tgfb1, Mmp2, and Timp2 genes expression, which contributed to a lower hydroxyproline concentration, lower collagen fiber organization, and to an improvement of the rats' gait 24 h after the injury. In conclusion, although the literature describes the benefic effect of GDF-5 for the tendon healing process, our results show that its application, isolated or associated with ADMSC, cannot improve the repair process of partial transected tendons, indicating the higher effectiveness of the application of ADMSC in injured Achilles tendons. Our results show that the application of ADMSC in injured Achilles tendons was more effective in relation to its association with GDF-5.

Avaliação do desempenho e satisfação dos usuários de próteses totais mucossuportadas fornecidas pelo Sistema Único de Saúde em município catarinense / Evaluation of performance and users satisfaction of complete denture prosthesis provided by the Unified Health System in Santa Catarina municipality

O edentulismo ainda e considerado um grande problema para a saúde publica, no Brasil. Acomete parte da população, em regiões distintas e diferentes faixas etárias. Alguns municípios brasileiros aderiram aos Laboratórios Regionais de Próteses Dentarias para minimizar essa condição; assim, buscou-se avaliar o desempenho e a satisfação dos usuários de próteses totais mucossuportadas fornecidas pelo Sistema Único de Saúde. Estudo transversal, de analise descritiva e abordagem quali-quantitativa, com amostra censitária de 115 usuários que receberam próteses totais superiores e/ou inferiores no período de julho de 2013 até julho de 2014. Foram aplicados os questionários OHIP-14 e a Escala Visual Analógica para avaliar a satisfação e desempenho. A idade mediana foi 59,0 (53,0-68,0) anos. Renda mensal prevalente foi de até um salário mínimo (60,0%; n=69). O grau de alfabetização mais comum foi ensino fundamental incompleto (68,7%; n=79). O desempenho mediano associado aos diferentes tipos de próteses foi de 99,0 para a superior, 95,0 para a inferior e 97,0 para ambas as próteses, resultados considerados estatisticamente significativos (p=0,047). Usuários do SUS que receberam próteses totais mucossuportadas estão satisfeitos com a reabilitação. Quanto ao desempenho das próteses avaliadas, constatou-se diferença estatisticamente significativa para reabilitação com prótese superior, inferior ou para ambas.

Edentulism is still considered a great problem for public health in Brazil. Affect the population in different regions and different ages. Some cities have joined the Regional Laboratories of Dental Prosthetics to minimize this condition, so it has been intended to evaluate the performance and user satisfaction of complete denture prosthesis provided by the Unified Health System. Cross-sectional study of descriptive analysis and qualitative and quantitative approach, with census sample of 115 users who have received upper and/ or lower complete dentures from July 2013 to July 2014. We applied the OHIP-14 questionnaire and Visual Analog Scale to assess satisfaction and performance. The median age was 59.0 (53.0 to 68.0) years. Prevalent monthly income was up to one minimum wage (60.0%; n = 69). The most common grade literacy was incomplete primary education (68.7%; n = 79). Average performance associated with different types of prosthesis was 99.0 for higher, 95.0 was lower and 97.0 for both prostheses, results were considered statistically significant (p = 0.047). SUS users who have received complete dentures prosthesis are satisfied with the rehabilitation. As for the performance of prosthesis assessed, there was no statistically significant difference for rehabilitation with upper dentures, lower or both.

Análise do conhecimento de pais ou responsáveis sobre a saúde bucal dos filhos com necessidades especiais / Analiysis of knowledge of parents or guardians about the oral health of their children with special needs

Introdução: Devido ao comprometimento físico ou mental, os pacientes com necessidades especiais apresentam dificuldades em realizar sua higiene bucal e assim muitos deles acabam recebendo auxílio de outra pessoa, seja um familiar ou cuidador. Objetivo: Buscou-se avaliar o conhecimento de pais ou responsáveis, sobre a saúde bucal dos seus filhos com necessidades especiais, em uma Clínica Odontológica Universitária Catarinense. Métodos: Foi realizado um estudo transversal, descritivo, com abordagem quantitativa. A população foi composta por pais ou responsáveis pelos pacientes que frequentaram uma Clínica Odontológica Universitária no município de Criciúma/SC, de agosto a setembro de 2016. Dos questionários aplicados, foram excluídos os que não estavam respondidos corretamente, resultando no total de 32 questionários. Resultados: Quanto à participação da higiene bucal dos pacientes, 51,6% auxiliam seus filhos. Observou-se que a prática da escovação dental ocorre de duas a três vezes ao dia em grande parte dos pacientes (71,9%; n=23), com relevância estatística (p<0,007). O esclarecimento sobre saúde bucal aos filhos é dado pelos pais ou responsáveis (78,1%), sendo mais frequentemente instruídos pela mãe (75,0%; n=18). Metade dos pais/responsáveis classificou a saúde bucal do seu filho como uma condição oral boa (50,0%). Entre os aspectos facilitadores relatados pelos responsáveis para manter a saúde bucal do PNE, 38,7% sugeriram a instalação de centros de referência habilitados e maior número de profissionais, além do trabalho multidisciplinar (19,4%). Conclusão: Os pais/responsáveis dos pacientes com necessidades especiais apresentaram conhecimento satisfatório sobre a saúde bucal de seus filhos.

Introduction: Due to the physical or mental impairment, patients with special needs have restrictions when performing their oral hygiene, so many of them end up getting help from another person, whether a relative or caregiver. Objective: We sought to evaluate the knowledge of parents or guardians on the oral health of their children with special needs in a University Dental Clinic in Santa Catarina. Methods: A transverse study, descriptive with quantitative approach was held. The population was composed by parents or responsibles by patients that attended the Dental Clinic at the University in the town of Criciúma/SC between August 2016 till September 2016. From the questionnaires applied were excluded the ones that were not answered correctly, resulting in the total of 32 questionnaires. Results: Regarding the oral hygiene of the patients, 51,6% help their children. Was observed that the practice of the dental brushing occurs twice to three times a day, a big part of the patients (71,9%; n = 23), with relevant statistics (p <0,007) the clarification about oral health to the children is given by parents or responsible (78,1%), being more frequently instructed by the mother (75,0%; n = 18). Half of the parents/ responsible rated the oral health condition of their children as good (50,0%). Between the aspects reported by the responsible for keeping the oral health of the patients with special needs, 38,7% claim on installing qualified referral centers and more professionals; beyond to the multidisciplinary work (19.4%). Conclusions: Parents and/or guardians of patients with special needs have satisfactory knowledge about the oral health of their children.

Effect of different resistance-training protocols on the extracellular matrix of the calcaneal tendon of rats.

The calcaneal tendon extracellular matrix (ECM) is composed of collagen, non-collagenous glycoproteins and proteoglycans, and able to adapt to various biomechanical stimuli. The objective of this study was to analyze the response of different resistance-training protocols, such as hypertrophy, strength and resistance, on the organization of the calcaneal tendon after training. Wistar rats were divided into four groups: untrained (UT), resistance training (RT), hypertrophy training (HT), and strength training (ST). The protocol in a vertical climbing platform was performed thrice per week over twelve weeks. For biochemical study, the tendons of each group were minced and analyzed for gelatinases, quantification of non-collagenous proteins, sulfated glycosaminoglycans, and hydroxyproline. For morphological analysis, sections were stained with HE and toluidine blue. Non-stained sections were used for birefringence analysis under polarization microscopy. The highest hydroxyproline concentrations were found in HT (154.8±14.2) and RT (173.6±25.2) compared with UT (122.4±27.0). A higher concentration of non-collagenous proteins was detected in the RT group (14.98mg/g) compared with the other groups. In polarization microscopy, major birefringence was observed in HT and the lowest in ST compared with UT, indicating higher organization of collagen bundles in HT. In analysis for zymography, the presence of latent MMP-9 was more prominent in the ST group and the active MMP-9 more prominent in the HT group. For MMP-2, significant differences in the latent isoform between the HT (184,867±6765) and UT (173,018±9696) groups were found. In sections stained with toluidine blue (TB), higher metachromasia was observed in the tendon's distal region in HT and RT groups, indicating a greater amount of proteoglycans. We conclude that the different training protocols produced different responses in the ECM. The remarkable presence of MMP-2 and -9 in the hypertrophy training group may be related to the highest organization of collagen bundles and possibly a more efficient remodeling process, observed in that group, as demonstrated by images and measurements of birefringence.

Achados citológicos em pacientes com captura híbrida positiva para papilomavírus humano em um laboratório de patologia de Criciúma / Citologic findings in patients with positive hybrid capture for human papillomavirus in a pathology laboratory in Criciúma

A infecção pelo HPV é a infecção sexualmente transmissível mais comum no mundo e está intimamente relacionada ao câncer de colo uterino. Acomete mulheres jovens sexualmente ativas com incidência de aproximadamente 25 a 45%. O objetivo do trabalho é conhecer os achados citológicos em pacientes com captura híbrida positiva para Papilomavírus humano em um laboratório de patologia de Criciúma, no período de junho de 2010 a maio de 2013. Foi realizado um estudo censitário, descritivo, observacional, transversal e quantitativo. A amostra foi composta por 75 mulheres com captura híbrida positiva para Papilomavírus humano e idade mediana de 27,0 anos (23,0 ­ 32,0). Observou-se que 96,0% (n=72) dos exames citopatológicos do colo uterino apresentaram resultado normal, enquanto 4,0% (n=3) demonstraram lesão cervical de baixo grau. Em relação ao resultado do teste de captura híbrida, notou-se infecção pelo subtipo viral de alto risco oncogênico em 66,6% (n=50) das pacientes. Não houve significância estatística (p=0,253) entre as variáveis idade e os subtipos virais de HPV encontrados na captura híbrida. Pode-se identificar a concordância com a literatura no que se refere à idade de maior prevalência de infecção pelo HPV, a maior proporção de exames citopatológicos normais dentre os infectados e o maior número de infecções por HPV de alto risco oncogênico. Nossos achados podem contribuir para futuros estudos visando avaliar o benefício custo-efetivo do teste de captura híbrida como método de rastreamento populacional do câncer de colo uterino.

The HPV infection is the most common sexually transmitted infection in the world and is closely related to cervical cancer. It affects young women who are sexually active with incidence of approximately 25-45 %. The objective is discover the cytological findings in patients with positive hybrid capture for human papillomavirus in a pathology laboratory in Criciuma, from the time period of June 2010 to May 2013. A census-based study, descriptive, observational, cross-sectional and quantitative. The sample consisted of 75 women with positive HPV hybrid capture and who are around the age of 27, 0 years old (23.0 to 32.0). It was observed that 96.0% (n = 72) of cervical screening showed normal results, while the other 4.0%(n = 3) demonstrated low-grade cervical lesion. In relation to the results of the hybrid capture test, it was noticed that infection by high- risk viral subtype HPV in 66.6% (n =50) of patients. There was no statistically breadth of significance (p = 0.253) between the variable age and subtypes of HPV found in the hybrid capture. You can identify the agreement with the literature as regards to the age of highest prevalence of HPV infection, the largest proportion of normal Pap smears from the infected and the largest number of infections by high oncogênico risk HPV. Our findings may contribute to future studies to evaluate the benefits of costeffective hybrid capture test as a method of populational screening of cervical cancer.

Perfil dos laudos de exames radiográficos intrabucais realizados no Sul Catarinense / Profile of reports of intraoral radiographs performed in the south of Santa Catarina state

Introdução: O exame radiográfico pode ser essencial para o diagnóstico das doenças bucais assintomáticas e na confirmação de sinais e sintomas clínicos. Buscou-se verificar o perfil epidemiológico dos pacientes, do Sistema Único de Saúde do município de Criciúma/SC, submetidos a exames radiográficos intrabucais, reali¬zados por uma clínica de radiologia odontológica particular. Objetivo: Buscou-se caracterizar os pacientes atendidos pelo Sistema Único de Saúde em um município Sul Catarinense, e submetidos a exames radiográ¬ficos intrabucais. Método: Foi realizado um estudo transversal, descritivo, com abordagem quantitativa, com uma amostra de 576 radiografias intrabucais, distribuídas em 290 laudos, no período de um ano. Resultados: A cárie (61,5%) foi a doença mais frequente e, entre os achados radiográficos, as cristas alveolares normais as mais prevalentes (43,7%). A doença cárie foi significativamente associada ao gênero (p=0,001), sendo mais frequente no feminino (58,7%). Houve associação estatisticamente significativa da idade dicotomizada em relação a cárie e as cristas alveolares normais (ambos com p<0,001), mais frequentes em indivíduos mais jovens. Conclusões: O perfil predominante foi composto por mulheres adultas de meia idade, a cárie foi a mais frequente entre as lesões e as cristas alveolares entre os achados radiográficos.

Introduction: Radiographic examination may be essential for the diagnosis of asymptomatic oral diseases and confirmation of clinical signs and symptoms. It was attempted to verify the epidemiological profile of patients, the Health System in the city of Criciuma/SC, submitted to intra-oral radiographic examinations by a private dental radiology clinic. Objective: It was attempted to verify the patients attended in the Sistema Único de Saúde in the South of Santa Catarina state, submited to intra-oral radiographs. Methods: It was conducted a cross-sectional descriptive study with a quantitative approach, from a sample of 576 intra-oral radiographs, distributed in 290 reports, within one year. Results: Caries (61.5%) were the most common disease and among the radiographic findings, normal alveolar ridges (43.7%). The caries was significantly associated with gender (p = 0.001), being more frequent in females (58.7%). There was a statistically significant association between dichotomized age in relation to decay and the normal alveolar ridges (both p <0.001), more common in younger individuals. Conclusions: The profile was composed of adult middle-aged women, caries were the most frequent among the injury and the alveolar ridges among the radiographic findings.

Prevalência de alterações bucais em pessoas com deficiência na clínica da Universidade do Extremo Sul Catarinense / Oral changes prevalence in persons with disability at the clinic of Universidade do extremo Sul Catarinense

Pessoas com deficiência são indivíduos que apresentam algum desvio de normalidade, podendo ser de ordem física, mental, sensorial, comportamental e/ou de crescimento, e que necessitam de cuidados diferenciados por um determinado período de tempo ou por toda a vida. Estudos que analisam o perfil epidemiológico de saúde bucal dos pacientes com necessidades especiais indicam alta prevalência de alterações como: cárie, edentulismo, traumatismo e de doença periodontal decorrente de uma higiene bucal precária. O objetivo deste estudo foi identificar a prevalência de alterações bucais em pacientes com necessidades especiais, atendidos na clínica de odontologia da Universidade do Extremo Sul Catarinense. Foi caracterizado como um estudo transversal, descritivo e quali-quantitativo, totalizando uma amostra de 73 prontuários de pacientes com idade entre 1 e 70 anos, predominantemente portadores de transtorno do espectro autista (23,3%). A pesquisa con-statou que 68,1% dos pesquisados apresentaram acometimento de cárie, 55,6% de ausências dentárias e 50% de tártaro. Concluiu-se que alterações bucais podem ser prevenidas ou minimizadas, através do trabalho da equipe multidisciplinar no manejo do paciente portador de necessidade especial e programa de prevenção em saúde bucal

Persons with disability are individuals who have some normality deviation that can be physical, mental, sen¬sory, behavioral and/or growth, which need special care for a certain period of time or for life. Studies that analyze the epidemiology of oral health of patients with special needs indicate high prevalence of alterations such as caries, tooth loss, trauma and periodontal disease resulting from a poor oral hygiene. The aim of this study was to identify the prevalence of oral abnormalities in patients with special needs attended at the dental clinic of UNESC. It was characterized as a cross-sectional, descriptive, qualitative and quantitative study, with a total sample of 73 records, ages from 1 to 70 years old, predominantly carriers of the autism spectrum (23.3%). The survey found that 68.1% of respondents had caries involvement, 55.6% dental absences and 50% tartar. It was concluded that oral diseases can be prevented or minimized through the work of the multidisciplinary team in the management of patients with special need, and prevention program in oral health

Tratamento endodôntico em dente desvitalizado por trauma: relato de caso clínico / Endodontic treatment in devitalized traumatized tooth: a case report

O objetivo deste trabalho é apresentar um relato de caso clínico de uma paciente com necessidade de tratamento endodôntico no elemento 41, com necropulpectomia decorrente de trauma de luxação. Paciente de 12 anos, gênero feminino, leucoderma, procurou atendimento na Clínica Universitária para tratar o dente traumatizado. Em exames clínicos e radiográficos, observou-se necrose e escurecimento coronário do elemento 41. Foi realizado tratamento endodôntico em duas sessões. O elemento foi instrumentado com sistema manual de limas até a K#50, irrigando-se com hipoclorito de sódio a 1% alternadamente com cada lima. Após o procedimento, foi realizada a irrigação final com ácido etilenodiamino tetra-acético a 17% e hipoclorito de sódio a 1%, e a secagem com pontas de papel estéreis. A obturação foi feita pela técnica de compactação lateral mais McSppaden (Ténica Híbrida de Tagger), utilizando-se cones de guta percha e cimento de óxido de zinco e eugenol. O caso está sendo proservado há 8 meses, sem sintomatologia, apresentando repleção endodôntica do conduto radicular com normalidade em região apical e redução do escurecimento coronário, segundo imagem periapical e acompanhamento radiográfico.

The aim of this study is to present a case report of a patient in need of endodontic treatment in the element 41, with necropulpectomy due to trauma. The patient was 12 years old, female, white skin, and she sought treatment at the University Odontologic Service to treat a traumatized tooth. In clinical and radiographic examination, there was necrosis and coronary darkening of the element 41. Endodontic treatment was conducted in two sessions. The element was instrumented with manual files system until K # 50, irrigating the canal with sodium hypochlorite 1% alternating with each file. After the procedure, the final irrigation was performed with ethylenediamine tetraacetic acid 17% and 1% sodium hypochlorite and drying with sterile paper points. The obturation was made by lateral compaction technique more McSppaden (Tagger Hybrid Technique), using gutta percha points and cement zinc oxide and eugenol. The case is being following 8 months without symptoms, with repletion of the endodontic root canal, normally in the apical region and reduction in coronary darkening, according periapical image and radiographic follow-up.

Complicações orais em pacientes tratados com radioterapia ou quimioterapia em um hospital de Santa Catarina / Oral complications in patients treated with radiotherapy or chemotherapy in a hospital in Santa Catarina

Objetivo: Este estudo se propôs a avaliar as complicações orais em pacientes tratados com radioterapia ou quimioterapia. Introdução: Mesmo que a radioterapia e a quimioterapia apresentem diminuição da taxa de mortalidade associada ao câncer, a morbidade relacionada ao tratamento pode levar a complicações sistêmicas importantes como, por exemplo, na região bucomaxilofacial, o que faz aumentar o tempo de internação e os custos do tratamento, bem como afetar diretamente a qualidade de vida dos pacientes oncológicos. Métodos: Foi realizado um estudo transversal, descritivo, observacional e de campo com uma amostra (por conveniência), composta por 96 pacientes, maiores de 18 anos, que estavam sob tratamento antineoplásico, no ambulatório de oncologia (radioterapia e quimioterapia) em um hospital de Santa Catarina. O estudo foi realizado nos meses de setembro e outubro de 2016. Os resultados indicaram a predominância de pacientes do gênero feminino, com o sistema reprodutor como o sítio oncológico mais encontrado, em maior proporção na idade de 56 a 65 anos, tratados com quimioterapia. Resultados: Foram encontrados 06 (seis) tipos de lesões, alterações ou patologias em 90% dos pacientes, destacando-se a xerostomia, a mucosite e a candidíase. Conclusões: A xerostomia, a mucosite e a candidíase foram as lesões mais encontradas nos pacientes. Tais problemas podem ser decorrentes da falta de tratamento odontológico antes da terapia oncológica, bem como durante o tratamento

Objective: This study aimed to evaluate oral complications in patients treated with radiotherapy or chemotherapy. Introduction: Although radiotherapy and chemotherapy have a reduction in cancer-associated mortality, treatment-related morbidity can lead to important systemic complications, such as in the mouth-maxillofacial region, which hospitalization and the costs of treatment, as well as directly affect the quality of life of cancer patients. Methods: A cross-sectional, descriptive, observational and field study was carried out with a sample (for convenience), composed of 96 patients, older than 18 years, who underwent antineoplastic treatment, at the oncology clinic (radiotherapy and chemotherapy) in a hospital of Santa Catarina. The study was conducted in September and October 2016. The results indicated the predominance of female patients, with the reproductive system as the most commonly found cancer site, at a greater proportion at age from 56 to 65 years, treated with chemotherapy. Results: Six (6) types of lesions, alterations or pathologies were found in 90% of the patients, with xerostomia, mucositis and candidiasis. Conclusions: Xerostomia, mucositis and candidiasis were the most frequent lesions in patients. Such problems may be due to the lack of dental treatment prior to oncologic therapy, as well as during this treatment

Data Mining Applied to Analysis of Contraceptive Methods Among College Students.

The aim of this study was to use the Data Mining to analyze the profile of the use of contraceptive methods in a university population. We used a database about sexuality performed on a university population in southern Brazil. The results obtained by the generated rules are largely in line with the literature and epidemiology worldwide, showing significant points of vulnerability in the university population. Validation measures of the study, as such, accuracy, sensitivity, specificity, and area under the ROC curve were higher or at least similar as compared to recent studies using the same methodology.

Accuracy of Decision Support Systems for Breast Cancer - Initial Results.

The aim of this study was to evaluate the accuracy of decision support systems in the diagnosis of breast cancer by means of a systematic review and meta-analysis of studies of diagnostic accuracy. The first step of the research, which consisted of the initial research of abstracts and titles identified from the research strategy in the databases was performed by two researchers independently. In this stage, 622 references were retrieved in the databases and, through a consensus meeting, 183 articles were selected for full reading.

Prevalência de maloclusão em crianças de 05 anos de idade em um município Catarinense / Prevalence of malocclusion in children, age five, in a municipality of Santa Catarina - Brazil

A maloclusão é atualmente um dos maiores problemas de saúde bucal, sendo superada apenas pelas doenças cárie e periodontal. Objetivo: Analisar a prevalência da maloclusão em escolares, de cinco anos de idade, em um município catarinense. Metodologia: Trata-se de um estudo transversal de análise de¬scritiva. Foi desenvolvido em cinco distritos de Criciúma (Centro, Santa Luzia, Próspera, Rio Maina e Quarta Linha) no período de fevereiro a abril de 2016. Foi aplicado um questionário semiestruturado aos pais e ex¬aminada a oclusão de seus filhos, totalizando a participação de 100 crianças. Resultados: No exame 50% das crianças necessitam algum tipo de intervenção ortodôntica nessa fase. As meninas apresentaram mais maloclusão (58%). A sobressaliência foi a mais prevalente e 100% das crianças que a apresentaram necessitam de intervenção ortodôntica. As crianças que não apresentaram sobressaliência (32,4%) também necessitam de intervenção, por outra maloclusão, associação estatisticamente significativa (p<0,001). Os pais possuem o ensino médio completo (40,2%), e renda mensal de 3 a 5 salários mínimos (46,7%). Conclusão: A maloclusão predominante foi a sobressaliência, seguida do apinhamento dental. Grande parte das crianças examinadas requer algum tipo de intervenção ortodôntica. São importantes a criação de políticas públicas e a implantação desse serviço pelo município em estudo, pois, com a intervenção ortodôntica precoce, melhores serão o prog¬nóstico e o impacto na qualidade de vida dessas crianças

The malocclusion is currently one of the largest oral health problems, only surpassed by caries and periodontal disease. Objective: To analyze the prevalence of malocclusion in students, five years old, in a municipality of Santa Catarina in Brazil. Methodology: This is a cross-sectional study with a descriptive analysis. It was developed in five Criciúma city districts (Centro, Santa Luzia, Próspera, Rio Maina and Quarta Linha) from February to April 2016. A semi-structured questionnaire was administered to parents and examined the occlusion of their children, totaling 100 children. Results: In the test 50% of children need some type of orthodontic intervention at this stage. Girls had more malocclusion (58%). The overjet was the most prevalent and 100% of children who presented, require orthodontic intervention. Children who did not have overjet (32.4%) also require intervention by other malocclusion, statistically significant association (p <0.001). Parents have completed high school (40.2%), and monthly income 3 to 5 minimum wages (46.7%). Conclusion: The predominant malocclusion was the overjet, followed by dental crowding. Much of the examined children

Utilização de pilares cerâmicos em prótese sobre implante: revisão de literatura / Ceramic abutments on implant supported tooth: a review

A implantodontia sofreu muitos avanços na Odontologia moderna. As restaurações estéticas implanto-supor¬tadas em dentes anteriores tornaram-se desafiadoras, pois os pilares protéticos utilizados para reter as próteses sobre implante são geralmente de titânio ou outros metais. Percebeu-se que esses implantes levam a uma coloração azul-acinzentada aos tecidos moles em pacientes com sorriso gengival ou biótipo fino. Para solu¬cionar esse problema, pilares em cerâmica de zircônia ou alumina podem ser utilizados para permitir a elimi¬nação de intercorrências quanto à cor e brilho metálico através do tecido peri-implantar. O resultado benéfico e a melhor adaptabilidade biológica e funcional estimulam o uso desses materiais. Esta revisão teve como finalidade descrever as principais características dos pilares cerâmicos, vantagens e desvantagens em relação aos metálicos, além das suas propriedades funcionais e biológicas.

The dental implant had many advances in modern dentistry. The implant-supported restorations in anterior teeth, have become challenging because the abutments used for retaining the prosthesis on implants are usu¬ally made of titanium or other metals. It was found that these implants lead to a blue-gray coloration on the soft tissue in patients with gingival smile or thin biotype. To solve this problem, ceramic abutments of zirconia or alumina may be used to allow the elimination of complications with regard to the color and metallic luster through the peri-implant tissues. The good result and the best biological and functional adaptability stimulate the use of these materials. This review aimed to describe the main characteristics of ceramic abutments, advan¬tages and disadvantages compared to the metal pillars, as also its functional and biological properties.

Extratos de plantas de uso popular contra infecções orais / Plant extracts of popular use against oral infections / Extractos de plantas de uso popular contra infecciones orales

Objetivo: Avaliar o efeito antibacteriano de extratos de plantas de uso popular sobre bactérias relacionadas ao desenvolvimento da cárie e infecções endodônticas. Métodos: Estudo experimental realizado na Universidade do Extremo Sul Catarinense, em 2015, no qual tinturas de Artemisia absinthium, Laurus nobilis, Bidens pilosa, Achillea millefolium L e Foeniculum vulgare, nas concentrações hidroalcoólicas de 5%, 10%, 15%, 20% em meio de cultura ágar Mueller Hinton, tiveram sua ação antibacteriana mensurada contra cepas de S. mutans e E. faecalis. Usou-se o método de difusão em meio sólido e a sensibilidade inibitória foi analisada pela presença e tamanho de halos de inibição, sendo grupo controle a clorexidina 0,12%. Utilizou-se nível de significância p<0,05. Resultados: Não houve inibição sobre a cepa de E. faecalis em nenhuma das tinturas, entretanto, observou-se efeito inibitório das tinturas de Artemisia absinthium, Laurus nobilis e Bidens pilosa sobre as cepas de S. mutans nas concentrações testadas. Conclusão: As tinturas de plantas de uso popular investigadas não apresentaram efeitos antimicrobianos sobre E. faecalis, causadora de infecções endodônticas, porém, três delas demonstraram efeitos inibitórios contra S. mutans, principal responsável pela cárie dentária.

Objetive: To assess the antibacterial effect of plant extracts of popular use on bacteria related to the development of caries and endodontic infections. Methods: Experimental study conducted at the University of the Extreme South of Santa Catarina in 2015 in which dyes of Artemisia absinthium, Laurus nobilis, Bidens pilosa, Achillea millefolium L and Foeniculum vulgare at hydro-alcoholic concentrations of 5%, 10%, 15% and 20% in Mueller Hinton agar growth-medium had their antibacterial activity against strains of S. mutans and E. faecalis measured. The solid medium diffusion method was used and the inhibitory activity was analyzed according to the presence and size of inhibition halos ­ control and chlorhexidine 0.12%. Significance level was set at α=0.05. Results: There was no inhibition on the strains of E. faecalis in any of the dyes; however, it was observed an inhibitory effect of Artemisia absinthium, Laurus nobilis and Bidens pilosa dyes on the strains of S. mutans at the concentrations tested. Conclusion: The dyes of plants of popular use assessed showed no antimicrobial effects on E. faecalis, which causes endodontic infections; however, three of them presented inhibitory effects against S. mutans, which is mainly responsible for caries.

Objetivo: Evaluar el efecto antibacteriano de extractos de plantas de uso popular sobre bacterias relacionadas al desarrollo de caries e infecciones endodónticas. Métodos: Estudio experimental realizado en la Universidad del Extremo Sur de Santa Catarina em 2015 en el cual tinturas de Artemisia absinthium, Laurus nobilis, Bidens pilosa, Achillea millefolium L y Foeniculum vulgare, em las concentraciones hidroalcohólicas del 5%, 10%, 15%, 20% en medio de cultivo agar Mueller Hinton, tuvieron su acción antibacteriana medida contra cepas de S. mutans e E. faecalis. Se utilizó el método de difusión en medio sólido y la sensibilidad inhibitoria fue analizada por la presencia y tamaño de halos de inhibición, teniendo como el grupo control la clorhexidina 0,12%. Se utilizó el nivel de significación de p<0,05. Resultados: No hubo inhibición sobre la cepa de E. faecalis en ninguna de las tinturas, sin embargo, se observó el efecto inhibitorio de las tinturas de Artemisia absinthium, Laurus nobilis y Bidens pilosa sobre las cepas de S. mutans en las concentraciones testadas. Conclusión: Las tinturas de plantas de uso popular investigadas no presentaron efectos antimicrobianos sobre el E. faecalis, causadora de infecciones endodónticas, sin embargo, tres de ellas han demostrado efectos inhibitorios contra el S. mutans, el principal responsable de la caries dentales.

Sistematização de um protocolo de atendimento clínico odontológico a gestantes em um Município Sul Catarinense / Systemization of a protocol of clinical dental care to pregnant women in a City South Catarinense

Introdução: A assistência odontológica para gestantes ainda sofre barreiras, pelos mitos e inverdades de que o tratamento odontológico venha causar algum dano à formação do bebê, uma vez que, nesse período, a cavidade bucal sofre alterações importantes, tornando o pré-natal odontológico um exame necessário. Méto¬dos: Foi elaborado um protocolo de atendimento a gestantes e entregue aos profissionais; antes da entrega foi aplicado um primeiro questionário e, transcorridos 60 dias, um segundo questionário foi aplicado para saber a eficácia e uso do protocolo. Resultados: 11 cirurgiões-dentistas participaram da pesquisa; a média de idade foi de 35,81 anos (±4,89). Por meio do 1° questionário 100% (n=11) se sentem seguros em atender as pacientes gestantes. Passados 60 dias o 2° questionário foi aplicado para analisar a satisfação quanto à utilização do protocolo. 55,50% (n=5) concordam que o protocolo deixou-os mais seguros em realizar os procedimen¬tos. Para 55,30% (n=6) o protocolo proporcionou satisfação profissional. Conclusão: O conhecimento dos cirurgiões-dentistas sobre as alterações que ocorrem na gravidez é importante para se realizar um atendimento mais seguro, assim, nosso trabalho mostrou que o uso de um protocolo clínico no dia a dia proporcionou mais segurança nos atendimentos, como também satisfação profissional aos cirurgiões-dentistas que utilizam o protocolo

Introduction: Dental care for pregnant women still suffers barriers, by the myths and untruths that the dental treatment will cause some damage the formation of the baby. During this period the oral cavity undergoes ma¬jor changes, making the dental Prenatal a necessary exam. Methods: A protocol of care for pregnant women and delivered to the professionals was drawn up before the delivery, a first questionnaire was applied and 60 days have elapsed after a second questionnaire was applied to know the effectiveness and use of the protocol. Results: 11 dental surgeons in the survey, the average age was 35.81 years (± 4.89). Through the 1st survey 100% (n = 11) feel safe to attend pregnant patients. After 60 days the 2nd questionnaire was applied to analyze the satisfaction regarding to the use of protocol, 55.50% (n = 5) agree that the protocol left them safer to perform the procedures, 55.30% (n = 6) that the protocol provided job satisfaction. Conclusion: Knowledge of dental surgeons about the changes that occur in pregnancy is important to realize a safer service; our study has shown the use of a clinical protocol for day-to-day provided more security in attendance, as well as job satisfaction to the dental surgeons who use the protocol